Pregabalin|Lurasidone|Bicalutamide|Enzalutamide--Jiangxi Jinfeng Pharmaceutical Co., Ltd.

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Product Center

Intermediates and Apis

Pregabalin
Product Name	CAS NO.	Structure	Specification	Production Scale
3-isobutylglutaric acid	75143-89-4		Off-white to white crystalline solid Purity≥99%	Commercial Scale
3-Isobutyl glutarimide/4-Isobutylpiperidine-2,6-dione	916982-10-0		Light yellow to off-white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
3-isobutylglutaric anhydride	185815-59-2		Brownish red liquid Purity≥98% Toluene≤2.0% Acetic acid≤0.8%	Commercial Scale
3-Carbamoymethyl-5-methylhexanoic acid	181289-15-6		Off-white to white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid	181289-33-8		White crystalline solid Purity≥99% Any single impurity≤0.5% ee≥99.5%	Commercial Scale
(S)-3-Cyano-5-methyl hexanoic acid ethyl ester	181289-39-4		Light yellow to colorless transparent liquid Purity≥99% Any single impurity≤0.3% ee≥99%	Commercial Scale

Lurasidone
Product Name	CAS NO.	Structure	Specification	Production Scale
Trans-1,2-Cyclohexanedicarboxylic acid	2305-32-0		Light yellow to off-white powder Purity≥98%	Commercial Scale
(1R,2R)-1,2-Cyclohexanedicarboxylic acid	46022-05-3		Off-white to white crystalline solid Purity≥98% Any single impurity≤1.0% ee≥99%	Commercial Scale
(1R,2R)-1,2-Cyclohexanedimethanol	65376-05-8		Off-white to white crystalline solid Purity≥99% Any single impurity≤0.5% ee≥99.5%	Commercial Scale

Bicalutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
4-Amino-2-(trifluoromethyl)benzonitrile	654-70-6		Off-white to white powder Purity≥99% Any single impurity≤0.2%	Commercial Scale
N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide	90357-53-2		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale
N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide	90357-51-0		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide	90356-78-8		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale

Enzalutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
Enzalutamide	915087-33-1		Off-white to white crystalline solid Purity≥99%	Pilot Scale
4-Bromo-2-fluoro-N-methylbenzamide	749927-69-3		Off-white to white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine	1289942-66-0		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester	1332524-01-2		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale
4-Isothiocyanato-2-(trifluoromethyl)benzonitrile	143782-23-4		Light yellow to off-white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
Methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate	1802242-47-2		Off-white to white crystalline powder Purity≥99% Any single impurity≤0.3%	Commercial Scale
Methyl 4-bromo-2-fluorobenzoate	179232-29-2		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale

Apalutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile	573762-62-6		Light brown to off-white powder Purity≥99% Any single impurity≤0.2%	Commercial Scale
4-((1-cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide	915087-26-2		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Pilot Scale
1-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylic acid	2170654-26-7/ 2227589-22-0		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Laboratory Scale
1-bromocyclobutanecarboxylic acid	32122-23-9		Off-white to white crystalline solid Purity≥98% Any single impurity≤0.5%	Laboratory Scale
Methyl 4-Amino-2-Fluorobenzoate	73792-08-2		Orange to brown solid Purity≥98% Any single impurity≤0.5%	Laboratory Scale
Methyl 1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylate	2227589-23-1		Off-white to white crystalline solid Purity≥99%	Laboratory Scale

Darolutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile	1297537-41-7		Off-white to white powder Purity≥98% Any single impurity≤0.5%	Pilot Scale
5-Acetyl-1H-Pyrazole-3-carboxylic acid	1297537-45-1		Light yellow to off-white powder Purity≥99% Any single impurity≤0.2%	Commercial Scale
2-Chloro-4-(1H-pyazol-3-yl)benzonitrile	1297537-37-1		Off-white to white powder Purity≥99% Any single impurity≤0.2%	Commercial Scale
5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-Pyrazole-3-carboxamide	1297537-33-7		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Laboratory Scale

Proxalutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
4-amino-3-fluoro-2-(trifluoromethyl)benzonitrile	1095188-12-7		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale

Ensitrelvir
Product Name	CAS NO.	Structure	Specification	Production Scale
3-tert-butyl-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione	1360105-53-8		Off-white to white powder Purity≥98%	Laboratory Scale
6-(ethylthio)-1-(2,4,5-trifluorobenzyl)-1,3,5-triazine-2,4(1H,3H)-dione	2771355-74-7		Off-white to white powder Purity≥98%	Laboratory Scale

Midazolam
Product Name	CAS NO.	Structure	Specification	Production Scale
2-Amino-5-chloro-2'-fluorobenzophenone	784-38-3		Yellow needle shaped crystalline solid Purity≥99.5% Any single impurity≤0.2%	Commercial Scale
2-chloro-N-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide	2836-40-0		Yellow needle shaped crystalline solid Purity≥99% Any single impurity≤0.5%	Laboratory Scale
7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one	2886-65-9		Light yellow to off-white crystalline solid Purity≥99% Any single impurity≤0.5%	Laboratory Scale

Tolvaptan
Product Name	CAS NO.	Structure	Specification	Production Scale
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one	160129-45-3		Light yellow to yellow crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one	137982-91-3		Light yellow to yellow crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one	137977-97-0		Light yellow to off-white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
2-Methyl-4-(2-methylbenzoylamino)benzoic acid	317374-08-6		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale

Mirogabalin
Product Name	CAS NO.	Structure	Specification	Production Scale
3-Ethylbicyclo[3.2.0]hept-3-en-6-one	1235479-59-0		Light yellow to colorless transparent liquid Purity≥98% Any single impurity≤0.5%	Commercial Scale

Conivaptan
Product Name	CAS NO.	Structure	Specification	Production Scale
1,2,3,4-Tetrahydro-benzo[b]azepin-5-one	1127-74-8		Light yellow to yellow crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
4-[(Biphenyl-2-ylcarbonyl)amino]benzoic acid	168626-74-2		Off-white to white solid Purity≥98% Any single impurity≤0.5%	Pilot Scale

Brivaracetam
Product Name	CAS NO.	Structure	Specification	Production Scale
3-propylpentanedioic acid	4165-98-4		Off-white to white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale

Iptacapon（LNP023）
Product Name	CAS NO.	Structure	Specification	Production Scale
4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoicacid	1644670-37-0		Off-white to white solid Purity≥99% Any single impurity≤0.5%	Pilot Scale
Methyl4-((2S,4S)-4-Ethoxypiperidin-2-Yl)Benzoate	1644667-62-8		Off-white to white solid Purity≥99% Any single impurity≤0.5%	Pilot Scale
5-Methoxy-7-Methyl-t-Boc-1H-indole-4-carbaldehyde	1481631-51-9		Off-white to white solid Purity≥98% Any single impurity≤0.5%	Pilot Scale

Torezolid
Product Name	CAS NO.	Structure	Specification	Production Scale
3-Fluoro-4-broMoaniline	656-65-5		Off-white to white crystalline solid Purity≥99%	Laboratory Scale

Drotaverin
Product Name	CAS NO.	Structure	Specification	Production Scale
3,4-Diethoxyphenylacetonitrile	27472-21-5		Off-white to white crystalline solid Purity≥98%	Laboratory Scale

Sitagliptin
Product Name	CAS NO.	Structure	Specification	Production Scale
2,4,5-Trifluorobenzyl chloride	243139-71-1		Light yellow to colorless transparent liquid Purity≥98%	Laboratory Scale
2,4,5-trifluorobenzyl bromide	157911-56-3		Light yellow transparent liquid Purity≥97%	Laboratory Scale

Others
Product Name	CAS NO.	Structure	Specification	Production Scale
2-trifluoromethyl-4-amino benzoic acid	393-06-6		Purity≥98%	Laboratory Scale

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